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A centrally acting opioid analgesic drug called tapentadol is used to treat moderate to severe pain. It is offered under several brand names, such as Palexia and Nucynta. In order to bind to opioid receptors in the brain and spinal cord and inhibit norepinephrine reuptake as well as mu-opioid receptor agonist activity, tapentadol functions. In cases of neuropathic pain, musculoskeletal pain, and postoperative pain, tapentadol is frequently recommended for pain management. Given its distinct mode of action and potential reduction in the incidence of certain adverse effects such as constipation and respiratory depression, it is seen as an alternative to other opioid medicines.