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Analgesics with central action, such as tramadol, are prescribed to treat moderate to severe pain. It is sold under several brand names, such as ConZip and Ultram. Among opioid drugs, tramadol is special because, like several antidepressants, it blocks the absorption of serotonin and norepinephrine in addition to acting as a mu-opioid receptor agonist. Pain related to musculoskeletal disorders, chronic pain, and postoperative pain are among the illnesses for which tramadol is frequently recommended. Off-label use for the treatment of neuropathic pain is also possible.
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